The Capacity of High-Grade Serous Ovarian Cancer Cells to Form Multicellular Structures Spontaneously along Disease Progression Correlates with Their Orthotopic Tumorigenicity in Immunosuppressed Mice

The Capacity of High-Grade Serous Ovarian Cancer Cells to Form Multicellular Structures Spontaneously along Disease Progression Correlates with Their Orthotopic Tumorigenicity in Immunosuppressed Mice

Many studies have examined the biology, genetics, and chemotherapeutic response of ovarian cancer’s solid component; its liquid facet, however, remains critically underinvestigated. Floating within peritoneal effusions known as ascites, ovarian cancer cells form multicellular structures, c...

Full description

Bibliographic Details
Main Authors: Alicia Goyeneche, Michael-Anthony Lisio, Lili Fu, Rekha Srinivasan, Juan Valdez Capuccino, Zu-hua Gao, Carlos Telleria
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
high-grade serous ovarian cancer
spheroids
aggregates
multicellular structures
peritoneal carcinomatosis
cancer biology
Online Access:https://www.mdpi.com/2072-6694/12/3/699

Similar Items

Similar Items