Quantifying compressive forces between living cell layers and within tissues using elastic round microgels
Increasing importance is placed upon the effect of mechanical forces on cell regulation, fate and disease states. Here, the authors describe a deformable fluorescent nanoparticle labeled elastic microsphere which can be used to calculate strain and traction forces in vitro and in vivo.
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2018-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-04245-1 |
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doaj-c72b3aa206494ddc9840377829e15d7e2021-05-11T10:25:45ZengNature Publishing GroupNature Communications2041-17232018-05-019111410.1038/s41467-018-04245-1Quantifying compressive forces between living cell layers and within tissues using elastic round microgelsErfan Mohagheghian0Junyu Luo1Junjian Chen2Gaurav Chaudhary3Junwei Chen4Jian Sun5Randy H. Ewoldt6Ning Wang7Laboratory for Cellular Biomechanics and Regenerative Medicine, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyLaboratory for Cellular Biomechanics and Regenerative Medicine, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyLaboratory for Cellular Biomechanics and Regenerative Medicine, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyDepartment of Mechanical Science and Engineering, University of Illinois at Urbana-ChampaignLaboratory for Cellular Biomechanics and Regenerative Medicine, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyDepartment of Mechanical Science and Engineering, University of Illinois at Urbana-ChampaignDepartment of Mechanical Science and Engineering, University of Illinois at Urbana-ChampaignLaboratory for Cellular Biomechanics and Regenerative Medicine, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and TechnologyIncreasing importance is placed upon the effect of mechanical forces on cell regulation, fate and disease states. Here, the authors describe a deformable fluorescent nanoparticle labeled elastic microsphere which can be used to calculate strain and traction forces in vitro and in vivo.https://doi.org/10.1038/s41467-018-04245-1 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Erfan Mohagheghian Junyu Luo Junjian Chen Gaurav Chaudhary Junwei Chen Jian Sun Randy H. Ewoldt Ning Wang |
| spellingShingle |
Erfan Mohagheghian Junyu Luo Junjian Chen Gaurav Chaudhary Junwei Chen Jian Sun Randy H. Ewoldt Ning Wang Quantifying compressive forces between living cell layers and within tissues using elastic round microgels Nature Communications |
| author_facet |
Erfan Mohagheghian Junyu Luo Junjian Chen Gaurav Chaudhary Junwei Chen Jian Sun Randy H. Ewoldt Ning Wang |
| author_sort |
Erfan Mohagheghian |
| title |
Quantifying compressive forces between living cell layers and within tissues using elastic round microgels |
| title_short |
Quantifying compressive forces between living cell layers and within tissues using elastic round microgels |
| title_full |
Quantifying compressive forces between living cell layers and within tissues using elastic round microgels |
| title_fullStr |
Quantifying compressive forces between living cell layers and within tissues using elastic round microgels |
| title_full_unstemmed |
Quantifying compressive forces between living cell layers and within tissues using elastic round microgels |
| title_sort |
quantifying compressive forces between living cell layers and within tissues using elastic round microgels |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2018-05-01 |
| description |
Increasing importance is placed upon the effect of mechanical forces on cell regulation, fate and disease states. Here, the authors describe a deformable fluorescent nanoparticle labeled elastic microsphere which can be used to calculate strain and traction forces in vitro and in vivo. |
| url |
https://doi.org/10.1038/s41467-018-04245-1 |
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