uPAR targeted phototheranostic metal-organic framework nanoprobes for MR/NIR-II imaging-guided therapy and surgical resection of glioblastoma

uPAR targeted phototheranostic metal-organic framework nanoprobes for MR/NIR-II imaging-guided therapy and surgical resection of glioblastoma

Glioblastoma (GBM) is the most malignant brain tumor. Owing to its highly infiltrative nature and restrictive blood-brain tumor barrier (BBTB), the current treatment strategies, including surgery and the following chemoradiotherapy, offer very low efficacy. Therefore, it is highly desirable to devel...

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Bibliographic Details
Main Authors: Zhike Li, Chenyuan Wang, Junrong Chen, Xiang Lian, Chuxiao Xiong, Rui Tian, Liefeng Hu, Xiaoxing Xiong, Jian Tian
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Materials & Design
Subjects:
Glioblastoma
Metal-organic framework
Near-infrared II fluorescence imaging
Photothermal therapy
Surgical navigation
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127520309229

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