Mitochondrial uptake of thiamin pyrophosphate: physiological and cell biological aspects.

Mitochondrial uptake of thiamin pyrophosphate: physiological and cell biological aspects.

Mammalian cells obtain vitamin B1 (thiamin) from their surrounding environment and convert it to thiamin pyrophosphate (TPP) in the cytoplasm. Most of TPP is then transported into the mitochondria via a carrier-mediated process that involves the mitochondrial thiamin pyrophosphate transporter (MTPPT...

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Bibliographic Details
Main Authors: Veedamali S Subramanian, Svetlana M Nabokina, Yaping Lin-Moshier, Jonathan S Marchant, Hamid M Said
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3758298?pdf=render

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