The NLRP3 Inflammasome and IL-1β Accelerate Immunologically Mediated Pathology in Experimental Viral Fulminant Hepatitis.
Viral fulminant hepatitis (FH) is a severe disease with high mortality resulting from excessive inflammation in the infected liver. Clinical interventions have been inefficient due to the lack of knowledge for inflammatory pathogenesis in the virus-infected liver. We show that wild-type mice infecte...
Main Authors: | Sheng Guo, Chengying Yang, Bo Diao, Xiaoyong Huang, Meihua Jin, Lili Chen, Weiming Yan, Qin Ning, Lixin Zheng, Yuzhang Wu, Yongwen Chen |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-09-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4569300?pdf=render |
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