Mechanisms of isoform specific Rap2 signaling during enterocytic brush border formation.

Mechanisms of isoform specific Rap2 signaling during enterocytic brush border formation.

Brush border formation during polarity establishment of intestinal epithelial cells is uniquely governed by the Rap2A GTPase, despite expression of the other highly similar Rap2 isoforms (Rap2B and Rap2C). We investigated the mechanisms of this remarkable specificity and found that Rap2C is spatiall...

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Bibliographic Details
Main Authors: Lucas J M Bruurs, Johannes L Bos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4159233?pdf=render

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