Research on pattern reversal visual evoked potential of children with spastic cerebral palsy

• Main Authors: Lu Li, Xiao-Jie Li, Yang Zhang, Hong-Bo Zhao
• Format: Article
• Language: English
• Published: Press of International Journal of Ophthalmology (IJO PRESS) 2015-07-01
• Series: Guoji Yanke Zazhi
• Subjects: cerebral palsy; visual evoked potential; visual impairment; the incubation period
• Online Access: http://ies.ijo.cn/cn_publish/2015/7/201507030.pdf

AIM: To explore the judgment of pattern reversal visual evoked potential on visual function and injured part of children with spastic cerebral palsy.<p>METHODS: There were two groups in this study. 30 children with spastic cerebral palsy(quadriplegia: 15, diplegia: 15)were selected as observation group, while 30 normal children were selected as control group with randomized controlled trial. The changes of half-view and full-view incubation period and amplitude were observed by pattern reversal visual evoked potential.<p>RESULTS: Full-view pattern reversal visual evoked potential: the P100 incubation period of the observation group was 113.55±8.14ms, and the P100 amplitude was 23.08±15.41μV. The P100 incubation period of the control group was 105.05±5.58ms, and the P100 amplitude was 31.65±7.37μV. From the comparison on P100 incubation and P100 amplitude between two groups, the difference was statistically significant(<i>P</i><0.05). P100 incubation period of the spastic diplegia of full-view pattern reversal visual evoked potential was 112.73±7.22ms, and the P100 amplitude was 21.03±12.17μV. P100 incubation period of the spastic quadriplegia was 114.37±9.02ms, and the P100 amplitude was 25.14±18.06μV. From the comparison on P100 incubation and P100 amplitude between two groups, the difference had no statistically significance(<i>P</i>>0.05). Compared to the control group, each eye and each view latency of observation group were higher, the difference was statistically significant(<i>P</i><0.05). The change of the incubation period of the full-view and half-view pattern reversal visual evoked potential took place in the lesion of the visual pathway: including optic neuropathy, some optic nerve lesion, lesion after optic chiasma, and optic chiasma lesion. Among them, the lesion after the optic chiasma was the most common. <p>CONCLUSION: Pattern reversal visual evoked potential can help people to understand the visual impairment and injury of children with spastic cerebral palsy in order to identify the abnormal children and early intervention.