The tissue-renin-angiotensin-system of the human intervertebral disc

Symptomatic intervertebral disc (IVD) degeneration accounts for significant socioeconomic burden. Recently, the expression of the tissue renin-angiotensin system (tRAS) in rat and bovine IVD was demonstrated. The major effector of tRAS is angiotensin II (AngII), which participates in proinflammatory...

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Bibliographic Details
Main Authors: Z Li, L Wystrach, A Bernstein, S Grad, M Alini, RG Richards, D Kubosch, N Südkamp, K Izadpanah, EJ Kubosch, G Lang
Format: Article
Language:English
Published: AO Research Institute Davos 2020-10-01
Series:European Cells & Materials
Subjects:
Online Access:https://www.ecmjournal.org/papers/vol040/pdf/v040a07.pdf