Selection and Characterization of DNA Aptamers for Egg White Lysozyme
We have selected aptamers binding to lysozyme from a DNA library using capillary electrophoresis-systematic evolution of ligands by exponential enrichment. During the selection process the dissociation constant of the ssDNA pool decreased from the micromolar to the low nanomolar range within five ro...
Main Authors: | Jeroen Lammertyn, Ann Van Schepdael, Jozef Anné, Elke Lammertyn, Jeroen Pollet, Kris P. F. Janssen, Dinh T. Tran |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-03-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/15/3/1127/ |
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