Considerations and Technical Pitfalls in the employment of the MTT Assay to Evaluate Photosensitizers for Photodynamic Therapy

Considerations and Technical Pitfalls in the employment of the MTT Assay to Evaluate Photosensitizers for Photodynamic Therapy

Photodynamic therapy (PDT) combines light, a photosensitizing chemical substance, and molecular oxygen to elicit cell death and is employed in the treatment of a variety of diseases, including cancer. The development of PDT treatment strategies requires in vitro assays to develop new photosensitizer...

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Bibliographic Details
Main Authors: Edith Alejandra Carreño, Anael Viana Pinto Alberto, Cristina Alves Magalhães de Souza, Heber Lopes de Mello, Andrea Henriques-Pons, Luiz Anastacio Alves
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Applied Sciences
Subjects:
MTT assay
cell MTT metabolic activity
photodynamic therapy
Online Access:https://www.mdpi.com/2076-3417/11/6/2603

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