Understanding the Physicochemical Properties of Mitragynine, a Principal Alkaloid of Mitragyna speciosa, for Preclinical Evaluation

Understanding the Physicochemical Properties of Mitragynine, a Principal Alkaloid of Mitragyna speciosa, for Preclinical Evaluation

Varied pharmacological responses have been reported for mitragynine in the literature, but no supportive scientific explanations have been given for this. These studies have been undertaken without a sufficient understanding of the physicochemical properties of mitragynine. In this work a UV spectro...

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Bibliographic Details
Main Authors: Surash Ramanathan, Suhanya Parthasarathy, Vikneswaran Murugaiyah, Enrico Magosso, Soo Choon Tan, Sharif Mahsufi Mansor
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Molecules
Subjects:
mitragynine
partition coefficient
pharmacology
pKa/pH
solubility
stability
Online Access:http://www.mdpi.com/1420-3049/20/3/4915

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