A FRET-based DNA biosensor tracks OmpR-dependent acidification of Salmonella during macrophage infection.

A FRET-based DNA biosensor tracks OmpR-dependent acidification of Salmonella during macrophage infection.

In bacteria, one paradigm for signal transduction is the two-component regulatory system, consisting of a sensor kinase (usually a membrane protein) and a response regulator (usually a DNA binding protein). The EnvZ/OmpR two-component system responds to osmotic stress and regulates expression of out...

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Bibliographic Details
Main Authors: Smarajit Chakraborty, Hideaki Mizusaki, Linda J Kenney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4397060?pdf=render

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