A FRET-based DNA biosensor tracks OmpR-dependent acidification of Salmonella during macrophage infection.
In bacteria, one paradigm for signal transduction is the two-component regulatory system, consisting of a sensor kinase (usually a membrane protein) and a response regulator (usually a DNA binding protein). The EnvZ/OmpR two-component system responds to osmotic stress and regulates expression of out...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-04-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC4397060?pdf=render |