Cytoskeletal Control and Wnt Signaling—APC’s Dual Contributions in Stem Cell Division and Colorectal Cancer

Intestinal epithelium architecture is sustained by stem cell division. In principle, stem cells can divide symmetrically to generate two identical copies of themselves or asymmetrically to sustain tissue renewal in a balanced manner. The choice between the two helps preserve stem cell and progeny po...

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Bibliographic Details
Main Author: M. Angeles Juanes
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
APC
Online Access:https://www.mdpi.com/2072-6694/12/12/3811