Bufalin-Loaded PEGylated Liposomes: Antitumor Efficacy, Acute Toxicity, and Tissue Distribution

Bufalin-Loaded PEGylated Liposomes: Antitumor Efficacy, Acute Toxicity, and Tissue Distribution

Abstract Bufalin, derived from Venenum Bufonis, exerts antitumor effects but has low bioavailability and adverse effects when administered as a single agent. The purpose of this study was to evaluate the physical and chemical properties, antitumor efficacy, general pharmacology, acute toxicity, and...

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Bibliographic Details
Main Authors: Jiani Yuan, Cheng Zeng, Wei Cao, Xuanxuan Zhou, Yang Pan, Yanhua Xie, Yifang Zhang, Qian Yang, Siwang Wang
Format: Article
Language:English
Published: SpringerOpen 2019-07-01
Series:Nanoscale Research Letters
Subjects:
Bufalin
Liposome
Tissue distribution
Antitumor efficacy
Acute toxicity
Online Access:http://link.springer.com/article/10.1186/s11671-019-3057-0

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