Crush injury to motor nerves in the G93A transgenic mouse model of amyotrophic lateral sclerosis promotes muscle reinnervation and survival of functionally intact nerve-muscle contacts

Crush injury to motor nerves in the G93A transgenic mouse model of amyotrophic lateral sclerosis promotes muscle reinnervation and survival of functionally intact nerve-muscle contacts

Selective survival of small motor nerve fibers and their neuromuscular contacts in the SOD1G93A transgenic mouse model of amyotrophic lateral sclerosis (ALS) suggests that smaller regenerated nerve fibers are more able to sustain reformed nerve-muscle connections as functionally intact motor units (...

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Bibliographic Details
Main Authors: P.S. Sharp, N. Tyreman, K.E. Jones, T. Gordon
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Neurobiology of Disease
Subjects:
Motor units
Muscle contractile forces
Motor unit size
Reinnervated muscle in ALS
Sprouting
Motor unit enlargement
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118300251

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http://www.sciencedirect.com/science/article/pii/S0969996118300251

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