Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis

Studies have established a relationship between hypothalamic-pituitary dysfunction and the onset of liver damage, which may occasionally progress to cirrhosis. Patients with hypopituitarism can develop a metabolic syndrome-like phenotype. Insulin resistance is the main pathophysiological axis of met...

Full description

Bibliographic Details
Main Authors: Marta Gonzalez Rozas, Lidia Hernanz Roman, Diego Gonzalez Gonzalez, José Luis Pérez-Castrillón
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2016/9071097
id doaj-c6d3f4f0a4af4da49d92766eb3e1f652
record_format Article
spelling doaj-c6d3f4f0a4af4da49d92766eb3e1f6522020-11-25T00:18:25ZengHindawi LimitedCase Reports in Endocrinology2090-65012090-651X2016-01-01201610.1155/2016/90710979071097Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver CirrhosisMarta Gonzalez Rozas0Lidia Hernanz Roman1Diego Gonzalez Gonzalez2José Luis Pérez-Castrillón3Internal Department, Hospital de Segovia, Segovia, SpainInternal Department, Hospital Universitario Río Hortega, Valladolid, SpainPathology Department, Hospital Universitario Río Hortega, Valladolid, SpainInternal Department, Hospital Universitario Río Hortega, Valladolid, SpainStudies have established a relationship between hypothalamic-pituitary dysfunction and the onset of liver damage, which may occasionally progress to cirrhosis. Patients with hypopituitarism can develop a metabolic syndrome-like phenotype. Insulin resistance is the main pathophysiological axis of metabolic syndrome and is the causal factor in the development of nonalcoholic fatty liver disease (NAFLD). We present the case of a young patient with liver cirrhosis of unknown aetiology that was finally attributed to panhypopituitarism.http://dx.doi.org/10.1155/2016/9071097
collection DOAJ
language English
format Article
sources DOAJ
author Marta Gonzalez Rozas
Lidia Hernanz Roman
Diego Gonzalez Gonzalez
José Luis Pérez-Castrillón
spellingShingle Marta Gonzalez Rozas
Lidia Hernanz Roman
Diego Gonzalez Gonzalez
José Luis Pérez-Castrillón
Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis
Case Reports in Endocrinology
author_facet Marta Gonzalez Rozas
Lidia Hernanz Roman
Diego Gonzalez Gonzalez
José Luis Pérez-Castrillón
author_sort Marta Gonzalez Rozas
title Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis
title_short Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis
title_full Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis
title_fullStr Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis
title_full_unstemmed Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis
title_sort panhypopituitarism due to absence of the pituitary stalk: a rare aetiology of liver cirrhosis
publisher Hindawi Limited
series Case Reports in Endocrinology
issn 2090-6501
2090-651X
publishDate 2016-01-01
description Studies have established a relationship between hypothalamic-pituitary dysfunction and the onset of liver damage, which may occasionally progress to cirrhosis. Patients with hypopituitarism can develop a metabolic syndrome-like phenotype. Insulin resistance is the main pathophysiological axis of metabolic syndrome and is the causal factor in the development of nonalcoholic fatty liver disease (NAFLD). We present the case of a young patient with liver cirrhosis of unknown aetiology that was finally attributed to panhypopituitarism.
url http://dx.doi.org/10.1155/2016/9071097
work_keys_str_mv AT martagonzalezrozas panhypopituitarismduetoabsenceofthepituitarystalkarareaetiologyoflivercirrhosis
AT lidiahernanzroman panhypopituitarismduetoabsenceofthepituitarystalkarareaetiologyoflivercirrhosis
AT diegogonzalezgonzalez panhypopituitarismduetoabsenceofthepituitarystalkarareaetiologyoflivercirrhosis
AT joseluisperezcastrillon panhypopituitarismduetoabsenceofthepituitarystalkarareaetiologyoflivercirrhosis
_version_ 1725376728112562176