Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer

Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer

Abstract Background Prostate cancer (PCa) remains a challenge worldwide. Due to the development of castration-resistance, traditional first-line androgen deprivation therapy (ADT) became powerlessness. Epidermal growth factor receptor (EGFR) is a well characterized therapeutic target to treat colore...

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Bibliographic Details
Main Authors: Yuning Liao, Zhiqiang Guo, Xiaohong Xia, Yuan Liu, Chuyi Huang, Lili Jiang, Xuejun Wang, Jinbao Liu, Hongbiao Huang
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Prostate cancer
EGFR
Spautin-1
Glut1
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s13046-019-1165-4

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