Early motor deficits in mouse disease models are reliably uncovered using an automated home-cage wheel-running system: a cross-laboratory validation
Deficits in motor function are debilitating features in disorders affecting neurological, neuromuscular and musculoskeletal systems. Although these disorders can vary greatly with respect to age of onset, symptomatic presentation, rate of progression and severity, the study of these disease models i...
Main Authors: | Silvia Mandillo, Ines Heise, Luciana Garbugino, Glauco P. Tocchini-Valentini, Alessandro Giuliani, Sara Wells, Patrick M. Nolan |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2014-03-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/7/3/397 |
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