Releasing the Lockdown: An Emerging Role for the Ubiquitin-Proteasome System in the Breakdown of Transient Protein Inclusions

Releasing the Lockdown: An Emerging Role for the Ubiquitin-Proteasome System in the Breakdown of Transient Protein Inclusions

Intracellular protein inclusions are diverse cellular entities with distinct biological properties. They vary in their protein content, sequestration sites, physiological function, conditions for their generation, and turnover rates. Major distinctions have been recognized between stationary amyloid...

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Bibliographic Details
Main Authors: Yuval Reiss, Elisheva Gur, Tommer Ravid
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomolecules
Subjects:
protein quality control
the ubiquitin-proteasome system
chaperones
misfolding
refolding
disaggregation
Online Access:https://www.mdpi.com/2218-273X/10/8/1168

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