Dysregulated Interferon Response Underlying Severe COVID-19

Innate immune interferons (IFNs), including type I and III IFNs, constitute critical antiviral mechanisms. Recent studies reveal that IFN dysregulation is key to determine COVID-19 pathogenesis. Effective IFN stimulation or prophylactic administration of IFNs at the early stage prior to severe COVID...

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Bibliographic Details
Main Authors: LeAnn Lopez, Peter C. Sang, Yun Tian, Yongming Sang
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/12/1433