Preparation of protein-loaded PLGA-PVP blend nanoparticles by nanoprecipitation method: entrapment, Initial burst and drug release kinetic studies

Preparation of protein-loaded PLGA-PVP blend nanoparticles by nanoprecipitation method: entrapment, Initial burst and drug release kinetic studies

Objective(s):Despite of wide range applications of polymeric nanoparticles in protein delivery, there are some problems for the field of protein entrapment, initial burst and controlled release profile.   Materials and Methods: In this study, we investigated the influence of some changes in PLGA nano...

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Bibliographic Details
Main Authors: Shahryar Shakeri, Rasoul Roghanian, Giti Emtiazi, Cesare Errico, Emo Chiellini, Federica Chiellini
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-07-01
Series:Nanomedicine Journal
Subjects:
Controlled release profile
FITC-HSA
Initial burst release
PLGA nanoparticles
Protein delivery
Online Access:http://nmj.mums.ac.ir/pdf_4473_4212cf2b2bfe94ae72065c19bc98272d.html

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