Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin

Patulin is a mycotoxin produced by many species of the fungi. The toxic action of patulin mainly affects the gastrointestinal tract and the immune system. The aim of our work was to assess the toxic effect of patulin, based on the analysis of interleukin IL-6 concentrations in the liver of test anim...

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Main Authors:	Borzecki Pawel, Borzecka Agnieszka, Chylinska-Wrzos Patrycja, Lis-Sochocka Marta, Wawryk-Gawda Ewelina, Jodlowska-Jedrych Barbara
Format:	Article
Language:	English
Published:	Sciendo 2019-03-01
Series:	Current Issues in Pharmacy and Medical Sciences
Subjects:	patulin mycotoxin interleukin 6 mice liver
Online Access:	https://doi.org/10.2478/cipms-2019-0008

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spelling	doaj-c6938b7a98334b94a44c469de2c382292021-09-06T19:22:04ZengSciendoCurrent Issues in Pharmacy and Medical Sciences2084-980X2300-66762019-03-01321343910.2478/cipms-2019-0008Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulinBorzecki Pawel0Borzecka Agnieszka1Chylinska-Wrzos Patrycja2Lis-Sochocka Marta3Wawryk-Gawda Ewelina4Jodlowska-Jedrych Barbara5Chair and Department of Histology and Embryology with Experimental Cytology Unit, Radziwillowska 11, 20-080Lublin, PolandChair and Department of Epidemiology and Clinical Research Methodology, Chodzki 1, 20-093Lublin, PolandChair and Department of Histology and Embryology with Experimental Cytology Unit, Radziwillowska 11, 20-080Lublin, PolandChair and Department of Histology and Embryology with Experimental Cytology Unit, Radziwillowska 11, 20-080Lublin, PolandChair and Department of Histology and Embryology with Experimental Cytology Unit, Radziwillowska 11, 20-080Lublin, PolandChair and Department of Histology and Embryology with Experimental Cytology Unit, Radziwillowska 11, 20-080Lublin, PolandPatulin is a mycotoxin produced by many species of the fungi. The toxic action of patulin mainly affects the gastrointestinal tract and the immune system. The aim of our work was to assess the toxic effect of patulin, based on the analysis of interleukin IL-6 concentrations in the liver of test animals loaded with different doses of this mycotoxin. The research was conducted on mice which were assigned to 6 groups receiving different doses of active substances. After decapitation, their livers were taken for laboratory testing.https://doi.org/10.2478/cipms-2019-0008patulinmycotoxininterleukin 6miceliver
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Borzecki Pawel Borzecka Agnieszka Chylinska-Wrzos Patrycja Lis-Sochocka Marta Wawryk-Gawda Ewelina Jodlowska-Jedrych Barbara
spellingShingle	Borzecki Pawel Borzecka Agnieszka Chylinska-Wrzos Patrycja Lis-Sochocka Marta Wawryk-Gawda Ewelina Jodlowska-Jedrych Barbara Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin Current Issues in Pharmacy and Medical Sciences patulin mycotoxin interleukin 6 mice liver
author_facet	Borzecki Pawel Borzecka Agnieszka Chylinska-Wrzos Patrycja Lis-Sochocka Marta Wawryk-Gawda Ewelina Jodlowska-Jedrych Barbara
author_sort	Borzecki Pawel
title	Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin
title_short	Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin
title_full	Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin
title_fullStr	Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin
title_full_unstemmed	Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin
title_sort	evaluation of interleukin-6 concentration in the liver of albino swiss mice after intoxication with various doses of patulin
publisher	Sciendo
series	Current Issues in Pharmacy and Medical Sciences
issn	2084-980X 2300-6676
publishDate	2019-03-01
description	Patulin is a mycotoxin produced by many species of the fungi. The toxic action of patulin mainly affects the gastrointestinal tract and the immune system. The aim of our work was to assess the toxic effect of patulin, based on the analysis of interleukin IL-6 concentrations in the liver of test animals loaded with different doses of this mycotoxin. The research was conducted on mice which were assigned to 6 groups receiving different doses of active substances. After decapitation, their livers were taken for laboratory testing.
topic	patulin mycotoxin interleukin 6 mice liver
url	https://doi.org/10.2478/cipms-2019-0008
work_keys_str_mv	AT borzeckipawel evaluationofinterleukin6concentrationintheliverofalbinoswissmiceafterintoxicationwithvariousdosesofpatulin AT borzeckaagnieszka evaluationofinterleukin6concentrationintheliverofalbinoswissmiceafterintoxicationwithvariousdosesofpatulin AT chylinskawrzospatrycja evaluationofinterleukin6concentrationintheliverofalbinoswissmiceafterintoxicationwithvariousdosesofpatulin AT lissochockamarta evaluationofinterleukin6concentrationintheliverofalbinoswissmiceafterintoxicationwithvariousdosesofpatulin AT wawrykgawdaewelina evaluationofinterleukin6concentrationintheliverofalbinoswissmiceafterintoxicationwithvariousdosesofpatulin AT jodlowskajedrychbarbara evaluationofinterleukin6concentrationintheliverofalbinoswissmiceafterintoxicationwithvariousdosesofpatulin
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Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin

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