Conditional RARα Knockout Mice Reveal Acute Requirement for Retinoic Acid and RARα in Homeostatic Plasticity

All-trans retinoic acid (RA) plays important roles in brain development through regulating gene transcription. Recently, a novel postdevelopmental role of RA in mature brain was proposed. Specifically, RA rapidly enhanced excitatory synaptic transmission independent of transcriptional regulation. RA...

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Bibliographic Details
Main Authors: Federica eSarti, Jessica eSchroeder, Jason eAoto, Lu eChen
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00016/full