A fast, miniaturised in-vitro assay developed for quantification of lipase enzyme activity

The discovery of allosteric modulators is a multi-disciplinary approach, which is time- and cost-intensive. High-throughput screening combined with novel computational tools can reduce these factors. Thus, we developed an enzyme activity assay, which can be included in the drug discovery work-flow s...

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Bibliographic Details
Main Authors: Ariane Menden, Davane Hall, Daniel Paris, Venkatarian Mathura, Fiona Crawford, Michael Mullan, Stefan Crynen, Ghania Ait-Ghezala
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:
Online Access:http://dx.doi.org/10.1080/14756366.2019.1651312