Porphyromonas gingivalis induces penetration of lipopolysaccharide and peptidoglycan through the gingival epithelium via degradation of junctional adhesion molecule 1.

Porphyromonas gingivalis is a major pathogen in severe and chronic manifestations of periodontal disease, which is one of the most common infections of humans. A central feature of P. gingivalis pathogenicity is dysregulation of innate immunity at the gingival epithelial interface; however, the mole...

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Bibliographic Details
Main Authors: Hiroki Takeuchi, Naoko Sasaki, Shunsuke Yamaga, Masae Kuboniwa, Michiya Matsusaki, Atsuo Amano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008124