Atorvastatin Inhibits Endothelial PAI-1-Mediated Monocyte Migration and Alleviates Radiation-Induced Enteropathy

Atorvastatin Inhibits Endothelial PAI-1-Mediated Monocyte Migration and Alleviates Radiation-Induced Enteropathy

Intestinal injury is observed in cancer patients after radiotherapy and in individuals exposed to radiation after a nuclear accident. Radiation disrupts normal vascular homeostasis in the gastrointestinal system by inducing endothelial damage and senescence. Despite advances in medical technology, t...

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Bibliographic Details
Main Authors: Seo Young Kwak, Sunhoo Park, Hyewon Kim, Sun-Joo Lee, Won-Suk Jang, Min-Jung Kim, SeungBum Lee, Won Il Jang, Ah Ra Kim, Eun Hye Kim, Sehwan Shim, Hyosun Jang
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
radiation-induced enteropathy
atorvastatin
plasminogen activator inhibitor-1
endothelial cell
monocyte migration
Online Access:https://www.mdpi.com/1422-0067/22/4/1828

Internet

https://www.mdpi.com/1422-0067/22/4/1828

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