Activated Erk Is an Early Retrograde Signal After Spinal Cord Injury in the Lamprey

Activated Erk Is an Early Retrograde Signal After Spinal Cord Injury in the Lamprey

We previously reported that spinal cord transection (TX) in the lamprey causes mRNA to accumulate in the injured tips of large reticulospinal (RS) axons. We sought to determine whether this mRNA accumulation results from phosphorylation and transport of retrograde signals, similar to what has been r...

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Bibliographic Details
Main Authors: Li-Qing Jin, Brittany H. John, Jianli Hu, Michael E. Selzer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Neuroscience
Subjects:
spinal cord injury
axon
retrograde signal
Erk
c-Jun
dynein
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.580692/full

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