Novel DNA Copy Number Losses in Chromosome 12g12-q13 in Adenoid Cystic Carcinoma

Novel DNA Copy Number Losses in Chromosome 12g12-q13 in Adenoid Cystic Carcinoma

In order to find common genetic abnormalities that may identify loci of genes involved in the development of adenoid cystic carcinoma (ACC), we investigated DNA copy number changes in 24 of these tumors by comparative genomic hybridization (CGH). Our results indicate that unlike many carcinomas, AC...

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Bibliographic Details
Main Authors: Wa'el El-Rifai, Sue Rutherford, Sakari Knuutila, Henry F. Frierson, jr., Christopher A. Moskaluk
Format: Article
Language:English
Published: Elsevier 2001-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
comparative genomic hybridization
loss of heterozygosity
microsatellite markers
genetic deletion
adenoid cystic carcinoma
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558601800403

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