Histone deacetylase 6 interference protects mice against experimental stroke-induced brain injury via activating Nrf2/HO-1 pathway

Histone deacetylase 6 interference protects mice against experimental stroke-induced brain injury via activating Nrf2/HO-1 pathway

Cerebral stroke is a fatal disease with increasing incidence. The study was to investigate the role and mechanism of Histone deacetylase 6 (HDAC6) on experimental stroke-induced brain injury. The recombinant shRNA-HDAC6 or scramble shRNA lentivirus was transfected to ICR mice. Then, the ischemia/rep...

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Bibliographic Details
Main Authors:	Jie Li, Yanping Zhao, Junfeng Shi, Zhanyun Ren, Feng Chen, Wuzhuang Tang
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2019-05-01
Series:	Animal Cells and Systems
Subjects:	Histone deacetylase 6 Nrf2/HO-1 cerebral ischemia/reperfusion injury oxidative stress
Online Access:	http://dx.doi.org/10.1080/19768354.2019.1601132

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