Histone deacetylase 6 interference protects mice against experimental stroke-induced brain injury via activating Nrf2/HO-1 pathway

Cerebral stroke is a fatal disease with increasing incidence. The study was to investigate the role and mechanism of Histone deacetylase 6 (HDAC6) on experimental stroke-induced brain injury. The recombinant shRNA-HDAC6 or scramble shRNA lentivirus was transfected to ICR mice. Then, the ischemia/rep...

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Bibliographic Details
Main Authors: Jie Li, Yanping Zhao, Junfeng Shi, Zhanyun Ren, Feng Chen, Wuzhuang Tang
Format: Article
Language:English
Published: Taylor & Francis Group 2019-05-01
Series:Animal Cells and Systems
Subjects:
Online Access:http://dx.doi.org/10.1080/19768354.2019.1601132