Tumor escape and progression of HER-2/neu negative breast cancer under immune pressure
<p>Abstract</p> <p>Background</p> <p>Emerging data from pre-clinical and clinical studies suggest that HER-2/neu-specific T cell responses could induce HER-2/neu antigen loss in the tumor cells. These data suggest that patients with HER-2/neu negative breast cancer migh...
Main Authors: | Wang Xiang-Yang, Wang Ena, Graham Laura, Ascierto Maria-Libera, Grimes Margaret M, Idowu Michael O, Payne Kyle K, Kmieciak Maciej, Bear Harry D, Manjili Masoud H |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-03-01
|
Series: | Journal of Translational Medicine |
Online Access: | http://www.translational-medicine.com/content/9/1/35 |
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