EFFECTIVENESS AND SAFETY OF REPEATED COURSES OF TREATMENT WITH RITUXIMAB IN PATIENTS WITH SEVERE REFRACTORY IDIOPATHIC ARTHRITIS

EFFECTIVENESS AND SAFETY OF REPEATED COURSES OF TREATMENT WITH RITUXIMAB IN PATIENTS WITH SEVERE REFRACTORY IDIOPATHIC ARTHRITIS

Show other versions (1)

The treatment of patients with severe juvenile idiopathic arthritis is difficult problem. The article presents the results of a study of effectiveness and safety of repeated courses of rituximab in 55 patients with different types of juvenile arthritis, resistant to infliximab and standard inmmunosu...

Full description

Bibliographic Details
Main Authors: E.I. Alexeeva, S.I. Valieva, T.M. Bzarova, E.L. Semikina, K.B. Isaeva, A.O. Lisitsin, R.V. Denisova, E.Yu. Gudkova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2009-09-01
Series:Voprosy Sovremennoj Pediatrii
Online Access:https://vsp.spr-journal.ru/jour/article/view/1164
id doaj-c647374e34394da7bf16f73ec4972433
record_format Article
spelling doaj-c647374e34394da7bf16f73ec49724332021-07-28T21:15:38Zeng"Paediatrician" Publishers LLC Voprosy Sovremennoj Pediatrii1682-55271682-55352009-09-018519301165EFFECTIVENESS AND SAFETY OF REPEATED COURSES OF TREATMENT WITH RITUXIMAB IN PATIENTS WITH SEVERE REFRACTORY IDIOPATHIC ARTHRITISE.I. Alexeeva0S.I. Valieva1T.M. Bzarova2E.L. Semikina3K.B. Isaeva4A.O. Lisitsin5R.V. Denisova6E.Yu. Gudkova7Scientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowScientific Center of Children’s Health, Russian Academy of Medical Sciences, MoscowThe treatment of patients with severe juvenile idiopathic arthritis is difficult problem. The article presents the results of a study of effectiveness and safety of repeated courses of rituximab in 55 patients with different types of juvenile arthritis, resistant to infliximab and standard inmmunosuppressive therapy. Remission of diseases was registered in 25% of patients after 1st course of treatment (24 weeks), in 52% — after 2nd course (48 weeks), in 75% — after 3rd course (72 weeks), and in 93% of patients after 4th course of treatment with rituximab (96 weeks).Key words: children, treatment, rituximab, B-cells, juvenile idiopathic arthritis.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(5):19-30)https://vsp.spr-journal.ru/jour/article/view/1164
collection DOAJ
language English
format Article
sources DOAJ
author E.I. Alexeeva
S.I. Valieva
T.M. Bzarova
E.L. Semikina
K.B. Isaeva
A.O. Lisitsin
R.V. Denisova
E.Yu. Gudkova
spellingShingle E.I. Alexeeva
S.I. Valieva
T.M. Bzarova
E.L. Semikina
K.B. Isaeva
A.O. Lisitsin
R.V. Denisova
E.Yu. Gudkova
EFFECTIVENESS AND SAFETY OF REPEATED COURSES OF TREATMENT WITH RITUXIMAB IN PATIENTS WITH SEVERE REFRACTORY IDIOPATHIC ARTHRITIS
Voprosy Sovremennoj Pediatrii
author_facet E.I. Alexeeva
S.I. Valieva
T.M. Bzarova
E.L. Semikina
K.B. Isaeva
A.O. Lisitsin
R.V. Denisova
E.Yu. Gudkova
author_sort E.I. Alexeeva
title EFFECTIVENESS AND SAFETY OF REPEATED COURSES OF TREATMENT WITH RITUXIMAB IN PATIENTS WITH SEVERE REFRACTORY IDIOPATHIC ARTHRITIS
title_short EFFECTIVENESS AND SAFETY OF REPEATED COURSES OF TREATMENT WITH RITUXIMAB IN PATIENTS WITH SEVERE REFRACTORY IDIOPATHIC ARTHRITIS
title_full EFFECTIVENESS AND SAFETY OF REPEATED COURSES OF TREATMENT WITH RITUXIMAB IN PATIENTS WITH SEVERE REFRACTORY IDIOPATHIC ARTHRITIS
title_fullStr EFFECTIVENESS AND SAFETY OF REPEATED COURSES OF TREATMENT WITH RITUXIMAB IN PATIENTS WITH SEVERE REFRACTORY IDIOPATHIC ARTHRITIS
title_full_unstemmed EFFECTIVENESS AND SAFETY OF REPEATED COURSES OF TREATMENT WITH RITUXIMAB IN PATIENTS WITH SEVERE REFRACTORY IDIOPATHIC ARTHRITIS
title_sort effectiveness and safety of repeated courses of treatment with rituximab in patients with severe refractory idiopathic arthritis
publisher "Paediatrician" Publishers LLC
series Voprosy Sovremennoj Pediatrii
issn 1682-5527
1682-5535
publishDate 2009-09-01
description The treatment of patients with severe juvenile idiopathic arthritis is difficult problem. The article presents the results of a study of effectiveness and safety of repeated courses of rituximab in 55 patients with different types of juvenile arthritis, resistant to infliximab and standard inmmunosuppressive therapy. Remission of diseases was registered in 25% of patients after 1st course of treatment (24 weeks), in 52% — after 2nd course (48 weeks), in 75% — after 3rd course (72 weeks), and in 93% of patients after 4th course of treatment with rituximab (96 weeks).Key words: children, treatment, rituximab, B-cells, juvenile idiopathic arthritis.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2009;8(5):19-30)
url https://vsp.spr-journal.ru/jour/article/view/1164
work_keys_str_mv AT eialexeeva effectivenessandsafetyofrepeatedcoursesoftreatmentwithrituximabinpatientswithsevererefractoryidiopathicarthritis
AT sivalieva effectivenessandsafetyofrepeatedcoursesoftreatmentwithrituximabinpatientswithsevererefractoryidiopathicarthritis
AT tmbzarova effectivenessandsafetyofrepeatedcoursesoftreatmentwithrituximabinpatientswithsevererefractoryidiopathicarthritis
AT elsemikina effectivenessandsafetyofrepeatedcoursesoftreatmentwithrituximabinpatientswithsevererefractoryidiopathicarthritis
AT kbisaeva effectivenessandsafetyofrepeatedcoursesoftreatmentwithrituximabinpatientswithsevererefractoryidiopathicarthritis
AT aolisitsin effectivenessandsafetyofrepeatedcoursesoftreatmentwithrituximabinpatientswithsevererefractoryidiopathicarthritis
AT rvdenisova effectivenessandsafetyofrepeatedcoursesoftreatmentwithrituximabinpatientswithsevererefractoryidiopathicarthritis
AT eyugudkova effectivenessandsafetyofrepeatedcoursesoftreatmentwithrituximabinpatientswithsevererefractoryidiopathicarthritis
_version_ 1721261530431881216

Similar Items