NF- κB Essential Modulator Deficiency Leading to Disseminated Cutaneous Atypical Mycobacteria

NF- κB Essential Modulator Deficiency Leading to Disseminated Cutaneous Atypical Mycobacteria

NF- κB essential modulator (NEMO) is a kinase integral to the macrophage TNF-α pathway, which leads to the intracellular destruction of Mycobacteria species. Defects in the NEMO pathway lead to a spectrum of diseases, including but not limited to ectodermal dysplasia, Mendelian susceptibility to myc...

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Bibliographic Details
Main Authors: Jonathan Braue, Vagishwari Murugesan, Steven Holland, Nishit Patel, Eknath Naik, Jennifer Leiding, Abraham Tareq Yacoub, Carlos N Prieto-Granada, John Norman Greene
Format: Article
Language:English
Published: PAGEPress Publications 2014-12-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Immunodeficiency, NEMO, rare diseases, mycobacterial Infections
Online Access:http://www.mjhid.org/index.php/mjhid/article/view/2089

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