Feedback activation of ferrous 5-lipoxygenase during leukotriene synthesis by coexisting linoleic acid

Feedback activation of ferrous 5-lipoxygenase during leukotriene synthesis by coexisting linoleic acid

Ferrous lipoxygenases seem to be activated through a feedback control mechanism via FA hydroperoxides generated from PUFAs by partially existing ferric lipoxygenases. However, during leukotriene synthesis, feedback activation of ferrous 5-lipoxygenase in the presence of arachidonic acid (AA) was not...

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Bibliographic Details
Main Authors:	Tokuko Takajo, Kazunori Tsuchida, Koichi Ueno, Ichiro Koshiishi
Format:	Article
Language:	English
Published:	Elsevier 2007-07-01
Series:	Journal of Lipid Research
Subjects:	isozyme pseudoperoxidase reaction hydroperoxides
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520425659

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