Biochemical alterations in diclofenac-treated rats: Effect of selenium on oxidative stress, inflammation, and hematological changes
We investigated the effect of selenium (Sel), a trace element in diclofenac sodium (DCF), nonsteroidal anti-inflammatory drugs-induced hepatic and renal toxicities in adult rats. Five experimental groups namely control, DCF (10 mg/kg), Sel (0.125 mg/kg), DCF + Sel (0.125 mg/kg), and DCF + Sel (0.25...
Main Authors: | Solomon E Owumi, Uche J Dim |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2019-09-01
|
Series: | Toxicology Research and Application |
Online Access: | https://doi.org/10.1177/2397847319874359 |
Similar Items
-
Manganese suppresses oxidative stress, inflammation and caspase-3 activation in rats exposed to chlorpyrifos
by: Solomon E. Owumi, et al.
Published: (2019-01-01) -
Quercetin abates induction of hepatic and renal oxidative damage, inflammation, and apoptosis in carbendazim-treated rats
by: Solomon E Owumi, et al.
Published: (2019-05-01) -
Effect of Resveratrol on Hematological and Biochemical Alterations in Rats Exposed to Fluoride
by: Nurgül Atmaca, et al.
Published: (2014-01-01) -
Silymarin mitigates diclofenac-induced liver toxicity through inhibition of inflammation and oxidative stress in male rats
by: Pantea Ramezannezhad, et al.
Published: (2019-07-01) -
Dichloromethane and ethanol co-exposure aggravates oxidative stress indices causing hepatic and renal dysfunction in pubertal rats.
by: Solomon E Owumi, et al.
Published: (2019-06-01)