The CCN Family Proteins: Modulators of Bone Development and Novel Targets in Bone-Associated Tumors
The CCN family of proteins is composed of six extracellular matrix-associated proteins that play crucial roles in skeletal development, wound healing, fibrosis, and cancer. Members of the CCN family share four conserved cysteine-rich modular domains that trigger signal transduction in cell adhesion,...
Main Authors: | Po-Chun Chen, Hsu-Chen Cheng, Shun-Fa Yang, Chiao-Wen Lin, Chih-Hsin Tang |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2014/437096 |
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