Spinal cord compression by a solitary metastasis from a low grade leydig cell tumour: a case report and review of the literature

<p>Abstract</p> <p>Background</p> <p>Leydig tumour is rare and there are only three cases with metastatic disease reported.</p> <p>Case presentation</p> <p>A 52 year-old Caucasian male was admitted, on emergency basis to the Orthopaedic Departmen...

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Main Authors: Lucas Jonathan D, Anbar Ashraf S, Samoladas Efthimios P, Fotiadis Hlias, Chalidis Byron E
Format: Article
Language:English
Published: BMC 2008-07-01
Series:World Journal of Surgical Oncology
Online Access:http://www.wjso.com/content/6/1/75
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spelling doaj-c61bd6d4444840359d336df0d52b2b2a2020-11-25T01:17:20ZengBMCWorld Journal of Surgical Oncology1477-78192008-07-01617510.1186/1477-7819-6-75Spinal cord compression by a solitary metastasis from a low grade leydig cell tumour: a case report and review of the literatureLucas Jonathan DAnbar Ashraf SSamoladas Efthimios PFotiadis HliasChalidis Byron E<p>Abstract</p> <p>Background</p> <p>Leydig tumour is rare and there are only three cases with metastatic disease reported.</p> <p>Case presentation</p> <p>A 52 year-old Caucasian male was admitted, on emergency basis to the Orthopaedic Department with six weeks history of increasing midthoracic back pain, change in gait, poor balance, subjective weakness and numbness of the lower trunk and legs. MRI scan showed change in the signal intensity of T4 and T5 vertebral body but their height were maintained. Urgent T4 and T5 corpectomies, decompression of the spinal cord and reconstruction of the vertebral bodies were performed followed by radiotherapy. Neurological status significantly improved with a mild residual numbness over the dorsum of the right foot. The histology of the excised tumour was identical to the primary. At 2 years follow-up visit the patient is neurologically stable and disease free without other organs metastases.</p> <p>Conclusion</p> <p>This is the first case in English literature, which shows that spinal metastases could occur even in the early stage of Leydig cell tumour, without other organs involvement. Aggressive surgical management of spinal metastases combined with post operative radiotherapy can give a better chance for long survivorship.</p> http://www.wjso.com/content/6/1/75
collection DOAJ
language English
format Article
sources DOAJ
author Lucas Jonathan D
Anbar Ashraf S
Samoladas Efthimios P
Fotiadis Hlias
Chalidis Byron E
spellingShingle Lucas Jonathan D
Anbar Ashraf S
Samoladas Efthimios P
Fotiadis Hlias
Chalidis Byron E
Spinal cord compression by a solitary metastasis from a low grade leydig cell tumour: a case report and review of the literature
World Journal of Surgical Oncology
author_facet Lucas Jonathan D
Anbar Ashraf S
Samoladas Efthimios P
Fotiadis Hlias
Chalidis Byron E
author_sort Lucas Jonathan D
title Spinal cord compression by a solitary metastasis from a low grade leydig cell tumour: a case report and review of the literature
title_short Spinal cord compression by a solitary metastasis from a low grade leydig cell tumour: a case report and review of the literature
title_full Spinal cord compression by a solitary metastasis from a low grade leydig cell tumour: a case report and review of the literature
title_fullStr Spinal cord compression by a solitary metastasis from a low grade leydig cell tumour: a case report and review of the literature
title_full_unstemmed Spinal cord compression by a solitary metastasis from a low grade leydig cell tumour: a case report and review of the literature
title_sort spinal cord compression by a solitary metastasis from a low grade leydig cell tumour: a case report and review of the literature
publisher BMC
series World Journal of Surgical Oncology
issn 1477-7819
publishDate 2008-07-01
description <p>Abstract</p> <p>Background</p> <p>Leydig tumour is rare and there are only three cases with metastatic disease reported.</p> <p>Case presentation</p> <p>A 52 year-old Caucasian male was admitted, on emergency basis to the Orthopaedic Department with six weeks history of increasing midthoracic back pain, change in gait, poor balance, subjective weakness and numbness of the lower trunk and legs. MRI scan showed change in the signal intensity of T4 and T5 vertebral body but their height were maintained. Urgent T4 and T5 corpectomies, decompression of the spinal cord and reconstruction of the vertebral bodies were performed followed by radiotherapy. Neurological status significantly improved with a mild residual numbness over the dorsum of the right foot. The histology of the excised tumour was identical to the primary. At 2 years follow-up visit the patient is neurologically stable and disease free without other organs metastases.</p> <p>Conclusion</p> <p>This is the first case in English literature, which shows that spinal metastases could occur even in the early stage of Leydig cell tumour, without other organs involvement. Aggressive surgical management of spinal metastases combined with post operative radiotherapy can give a better chance for long survivorship.</p>
url http://www.wjso.com/content/6/1/75
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