Metastasis of breast cancer to bladder

• Main Authors: Asma Hadhri, Rim Abidi, Najet Mahjoub, Alia Mousli, Khalil Mahjoubi, Nadia Boujelbene, Chiraz Nasr
• Format: Article
• Language: English
• Published: SpringerOpen 2021-08-01
• Series: African Journal of Urology
• Subjects: Breast cancer; Bladder metastasis; Prognosis; Case report
• Online Access: https://doi.org/10.1186/s12301-021-00224-z

Abstract Background Breast cancer is the leading cause of cancer death in women, and most breast cancer related deaths are due to metastasis. Urinary bladder metastasis from breast cancer is rarely reported in the literature. Case presentation We report a case of a 77-year-old female with history of left breast cancer, who presented a thickening of the bladder wall at pelvic ultrasound. Biopsy confirmed that the origin was lobular carcinoma of breast origin. The patient received chemotherapy, but the clinical course of the patient was very aggressive and she died one year later. Conclusion Bladder metastasis from breast cancer is rare, but the literature reveals an increase in such occurrence over the last few years. Pathologic diagnosis relies on immunohistochemical studies. Chemotherapy and hormonal treatment represent the standard therapy, with radiotherapy being used only to control bladder bleeding. The prognosis is usually poor.