Sumoylation Negatively Regulates CSR1-Dependent Prostate Cancer Cell Death

Sumoylation Negatively Regulates CSR1-Dependent Prostate Cancer Cell Death

Background/Aims: SUMOylation is a dynamic process and reversed by the activity of SUMO-specific proteases (SENPs) family. SENP1, a member of this family, is highly expressed and plays oncogenic roles in diverse cancers including prostate cancer. However, the SENP1-transgenic mice exhibit aberrant tr...

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Bibliographic Details
Main Authors: Hua-Rong Luo, Ying Liu, Xiao-Dong Wan, Jun-Liang Li, Min Wu, Qi-Min Zhang, Deng-Long Wu, Xin Zhao, Tian-Ru Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Sumoylation
SUMO-specific protease 1
Cellular Stress Response 1
Ubiquitination
Online Access:https://www.karger.com/Article/FullText/489370

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https://www.karger.com/Article/FullText/489370

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