The Effect of C-Terminal Helix on the Stability of FF Domain Studied by Molecular Dynamics Simulation

The Effect of C-Terminal Helix on the Stability of FF Domain Studied by Molecular Dynamics Simulation

To investigate the effect of C-terminal helix on the stability of the FF domain, we studied the native domain FF3-71 from human HYPA/FBP11 and the truncated version FF3-60 with C-terminal helix being deleted by molecular dynamics simulations with GROMACS package and GROMOS 43A1 force field. The resu...

Full description

Bibliographic Details
Main Authors: Jihua Wang, Zanxia Cao, Liling Zhao
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:International Journal of Molecular Sciences
Subjects:
FF domain
molecular dynamics simulation
C-terminal helix
structural stability
intermediate state
Online Access:http://www.mdpi.com/1422-0067/13/2/1720/

Internet

http://www.mdpi.com/1422-0067/13/2/1720/

Similar Items