Screening of Human CYP1A2 and CYP3A4 Inhibitors from Seaweed In Silico and In Vitro

Phenolic compounds and carotenoids are potential inhibitors of cytochrome P450s. Sixteen known compounds, phenolic compounds and carotenoids from seaweed were examined for potential inhibitory capacity against CYP1A2 and CYP3A4 in silico and in vitro. Morin, quercetin, and fucoxanthin inhibited the...

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Bibliographic Details
Main Authors: Sung-Kun Yim, Kian Kim, SangHo Chun, TaeHawn Oh, WooHuk Jung, KyooJin Jung, Chul-Ho Yun
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/18/12/603