Differential requirements of two recA mutants for constitutive SOS expression in Escherichia coli K-12.

Repairing DNA damage begins with its detection and is often followed by elicitation of a cellular response. In E. coli, RecA polymerizes on ssDNA produced after DNA damage and induces the SOS Response. The RecA-DNA filament is an allosteric effector of LexA auto-proteolysis. LexA is the repressor of...

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Bibliographic Details
Main Authors: Jarukit Edward Long, Nicholas Renzette, Richard C Centore, Steven J Sandler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2605550?pdf=render

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