Differential requirements of two recA mutants for constitutive SOS expression in Escherichia coli K-12.
Repairing DNA damage begins with its detection and is often followed by elicitation of a cellular response. In E. coli, RecA polymerizes on ssDNA produced after DNA damage and induces the SOS Response. The RecA-DNA filament is an allosteric effector of LexA auto-proteolysis. LexA is the repressor of...
Main Authors: | Jarukit Edward Long, Nicholas Renzette, Richard C Centore, Steven J Sandler |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2605550?pdf=render |
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