Metabolism of crystals within the joint

Monosodium urate (MSU), calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals deposit in joints and surrounding tissues causing acute inflammation and chronic cartilage damage. A number of endogenous substances and physicochemical conditions affect their precipitation, gr...

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Main Authors: A. Scanu, F. Oliviero, L. Punzi
Format: Article
Language:English
Published: PAGEPress Publications 2012-01-01
Series:Reumatismo
Subjects:
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/563
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spelling doaj-c5e58560858f4b0d9f62cdf3102d7e702020-11-24T20:46:14ZengPAGEPress PublicationsReumatismo0048-74492240-26832012-01-0163422122910.4081/reumatismo.2011.221Metabolism of crystals within the jointA. ScanuF. OlivieroL. PunziMonosodium urate (MSU), calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals deposit in joints and surrounding tissues causing acute inflammation and chronic cartilage damage. A number of endogenous substances and physicochemical conditions affect their precipitation, growth and even dissolution, regulating their metabolism and inflammatory activity. We review how MSU and calcium crystals form within the joints and the various factor which regulate their formation.http://www.reumatismo.org/index.php/reuma/article/view/563monosodium urate, pyrophosphate, basic calcium phosphate, crystals, metabolism
collection DOAJ
language English
format Article
sources DOAJ
author A. Scanu
F. Oliviero
L. Punzi
spellingShingle A. Scanu
F. Oliviero
L. Punzi
Metabolism of crystals within the joint
Reumatismo
monosodium urate, pyrophosphate, basic calcium phosphate, crystals, metabolism
author_facet A. Scanu
F. Oliviero
L. Punzi
author_sort A. Scanu
title Metabolism of crystals within the joint
title_short Metabolism of crystals within the joint
title_full Metabolism of crystals within the joint
title_fullStr Metabolism of crystals within the joint
title_full_unstemmed Metabolism of crystals within the joint
title_sort metabolism of crystals within the joint
publisher PAGEPress Publications
series Reumatismo
issn 0048-7449
2240-2683
publishDate 2012-01-01
description Monosodium urate (MSU), calcium pyrophosphate dihydrate (CPPD) and basic calcium phosphate (BCP) crystals deposit in joints and surrounding tissues causing acute inflammation and chronic cartilage damage. A number of endogenous substances and physicochemical conditions affect their precipitation, growth and even dissolution, regulating their metabolism and inflammatory activity. We review how MSU and calcium crystals form within the joints and the various factor which regulate their formation.
topic monosodium urate, pyrophosphate, basic calcium phosphate, crystals, metabolism
url http://www.reumatismo.org/index.php/reuma/article/view/563
work_keys_str_mv AT ascanu metabolismofcrystalswithinthejoint
AT foliviero metabolismofcrystalswithinthejoint
AT lpunzi metabolismofcrystalswithinthejoint
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