Development of a Rapid and Sensitive HPLC Assay Method for Lenalidomide Capsules and Its Related Substances

Development of a Rapid and Sensitive HPLC Assay Method for Lenalidomide Capsules and Its Related Substances

A chromatographic method was established for the determination of lenalidomide and related substances in 10 mg and 5 mg capsules using Sunfire C-18(250×4.6 mm ID, 5 μm) HPCL column with 85:15 v/v ratio of mobile phases A (mixture of phosphoric acid buffer and 1-octane sulphonic acid sodium salt) and...

Full description

Bibliographic Details
Main Authors:	L. Maheshwara Reddy, K. Janardhan Reddy, L. Bhaskar Reddy, P. Raveendra Reddy
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	E-Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2012/673736

Similar Items

A simple RP-HPLC method for related substances of zoledronic acid in pharmaceutical products
by: L. Maheswara Reddy, et al.
Published: (2017-02-01)

Estimation of Ziprasidone Hydrochloride Monohydrate in Bulk and Capsules by Reverse Phase HPLC
by: B. Sudha Rani, et al.
Published: (2006-01-01)

A highly sensitive fluorimetric method for determination of lenalidomide in its bulk form and capsules via derivatization with fluorescamine
by: Darwish Ibrahim A, et al.
Published: (2012-10-01)

Development of a reversed-phase HPLC method for determination of related impurities of Lenalidomide
by: Seyyed Amir Siadati, et al.
Published: (2020-04-01)

Comparison of microbiological assay and HPLC-UV for determination of fluconazole in capsules
by: Kelly Marques Queiroz, et al.
Published: (2009-12-01)

Computer-Aided Rapid Establishment of Fingerprint of Xiaojin Capsule by HPLC
by: Hui Jiang, et al.
Published: (2021-01-01)

Magnetic resonance diagnosis of adhesive capsulitis of the shoulder
by: Reddy Ravikanth, et al.
Published: (2019-01-01)

Validation and Stability Indicating RP-HPLC Method for the Determination of Sildenafil Citrate in Pharmaceutical Formulations and Human Plasma
by: B. Prasanna Kumar Reddy, et al.
Published: (2008-01-01)

A Rapid and Direct Sensitive Spectrophotometric Method for the Determination of Molybdenum(VI) using Gallacetophenone Phenylhydrazone with Application to Alloy Steel Samples
by: D. Venkataramana Reddy, et al.
Published: (2011-01-01)

Ameliorating the antitumor activity of lenalidomide using PLGA nanoparticles for the treatment of multiple myeloma
by: Veera Venkata Satyanarayana Reddy Karri, et al.
Published: (2017-06-01)

Synthesis of related substances of olmesartan medoxomil, an anti-hypertensive drug
by: Karrothu S. Babu, et al.
Published: (2010-05-01)

Determination of Pantoprazole Sodium and Lansoprazole in Individual Tablet Dosage Forms by RP-HPLC Using Single Mobile Phase
by: B. Prasanna Kumar Reddy, et al.
Published: (2009-01-01)

Low Power Real-time Video and Audio Embedded System Design for Naturalistic Bicycle Study
by: Karri, Janardhan Bhima Reddy
Published: (2015)

Carfilzomib-lenalidomide-dexamethasone in the management of lenalidomide-refractory multiple myeloma
by: C. Cerchione, et al.
Published: (2020-10-01)

Related substance determination of formononetin by HPLC
by: Xingyan PAN, et al.
Published: (2017-02-01)

Development and Validation of a Specific Stability Indicating High Performance Liquid Chromatographic Methods for Related Compounds and Assay of Solifenacin Succinate
by: B. V. Rami Reddy, et al.
Published: (2013-01-01)

Distal perforator based cross leg flaps for leg and foot defects
by: V Bhattacharya, et al.
Published: (2005-01-01)

DETERMINATION OF RELATED IMPURITIES IN THE ANILOCAINE SUBSTANCE BY HPLC METHOD
by: D. R. Sabirzyanov, et al.
Published: (2017-08-01)

Mechanism of action of lenalidomide in hematological malignancies
by: Kotla Venumadhav, et al.
Published: (2009-08-01)

A Simple and Sensitive RP-UPLC Method for the Simultaneous Determination of N-Hydroxybenzotriazole, Cinchonidine and 1,3-Dicyclohexyl Urea Contents in Fosinopril Sodium Drug Substance
by: M. Narendra Kumar, et al.
Published: (2012-01-01)

An analytical “quality by design” approach in RP-HPLC method development and validation for reliable and rapid estimation of irinotecan in an injectable formulation
by: Bhaskaran Navya Ajitkumar, et al.
Published: (2021-03-01)

Evaluation of 2,6-diacetylpyridinebis-4-phenyl-3-thiosemicarbazone as complexing reagent for zinc in food and environmental samples
by: S. Adi Narayana Reddy, et al.
Published: (2016-09-01)

Obsessive-compulsive and related disorders in international classification of Diseases-11 and its relation to international classification of Diseases-10 and diagnostic and statistical manual of mental Disorders-5
by: Y C Janardhan Reddy, et al.
Published: (2018-01-01)

Radiation and mass transfer effects on unsteady MHD free convection flow of an incompressible viscous fluid past a moving vertical cylinder
by: Gnaneswara Reddy M., et al.
Published: (2009-01-01)

Is there a role for immunological mechanisms in etiopathogenesis of obsessive compulsive disorder?
by: Naren P Rao, et al.
Published: (2013-01-01)

A new simple and rapid validated RP-HPLC method for determination of ziprasidone in ziprasidone capsules
by: Ruchi Bansal, et al.
Published: (2016-09-01)

Analytical Quality by Design Approach to Test Method Development and Validation in Drug Substance Manufacturing
by: N. V. V. S. S. Raman, et al.
Published: (2015-01-01)

Carbohydrate analysis of Simmondsia chinensis (Link) Schneider and its relation to rooting
by: Reddy, Steven Jeffrey
Published: (1980)

Stability Studies Of CdTe/CdS Thin Film Solar Cells
by: Tetali, Bhaskar Reddy
Published: (2005)

Development of new rotation concept for rock drills
by: Bhaskar Reddy, Akepati
Published: (2015)

Rapid Diagnosis of Pulmonary and Extrapulmonary Tuberculosis in HIV-Infected Patients. Comparison of LED Fluorescent Microscopy and the GeneXpert MTB/RIF Assay in a District Hospital in India
by: Gerardo Alvarez-Uria, et al.
Published: (2012-01-01)

STABILITY INDICATING AND COMPARATIVE ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF MEMANTINE HCl BY RP-HPLC AND UV SPECTROPHOTOMETRY
by: Bannimath, G., et al.
Published: (2021)

Can the Xpert MRSA/SA BC assay be used as an antimicrobial stewardship tool? A prospective assay validation and descriptive impact assessment study in a South African setting
by: Kessendri Reddy, et al.
Published: (2021-02-01)

The effect of environment on post surgical overall well-being and pain sensitivity in an animal model
by: Reddy, Archana
Published: (2016)

Mass Transfer and MHD Effects on Unsteady Porous Stretching Surface Embedded in a Porous Medium With Variable Heat Flux in The Presence of Heat Source
by: G.V. Ramana REDDY, et al.
Published: (2013-01-01)

Substantiation of conditions for determination of related substances in bisoprolol fumarate by HPLC
by: O. A. Baturina, et al.
Published: (2018-02-01)

Glucocorticoid Receptor α Mediates Roflumilast’s Ability to Restore Dexamethasone Sensitivity in COPD
by: Reddy AT, et al.
Published: (2020-01-01)

Determination of related substances in lisinopril and amlodipine tablets by HPLC
by: Dao-Rui Yu, et al.
Published: (2016-06-01)

Assay of Drugs by HPLC
by: 李青
Published: (2003)

Evaluation of (HPLC) Patterns of Sickle Cell Anaemia patients in comparison with apparently healthy individuals
by: R Manasa Reddy1 , Srilatha K 2
Published: (2017-12-01)

Cannot write session to /tmp/vufind_sessions/sess_kcijoh9qgai6vg6pna36oqlgh5