Facile design of lidocaine-loaded polymeric hydrogel to persuade effects of local anesthesia drug delivery system: complete in vitro and in vivo toxicity analyses

Facile design of lidocaine-loaded polymeric hydrogel to persuade effects of local anesthesia drug delivery system: complete in vitro and in vivo toxicity analyses

The principal goal of the present investigation was to enterprise new and effective drug delivery vesicle for the sustained delivery of local anesthetic lidocaine hydrochloride (LDC), using a novel combination of copolymeric hydrogel with tetrahydroxyborate (COP–THB) to improve bioactivity and thera...

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Bibliographic Details
Main Authors: Yan Li, Erxian Zhao, Li Li, Liying Bai, Wei Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Drug Delivery
Subjects:
hydrogel
ldc
in vitro release
l929 cells
in vivo evaluations
drug delivery
Online Access:http://dx.doi.org/10.1080/10717544.2021.1931558

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