Infection of Human Monocytes with Leishmania infantum Strains Induces a Downmodulated Response when Compared with Infection with Leishmania braziliensis

Infection of Human Monocytes with Leishmania infantum Strains Induces a Downmodulated Response when Compared with Infection with Leishmania braziliensis

Human infection with different species of Leishmania leads to distinct clinical manifestations, ranging from relatively mild cutaneous (Leishmania braziliensis) to severe visceral (Leishmania infantum) forms of leishmaniasis. Here, we asked whether in vitro infection of human monocytes by Leishmania...

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Bibliographic Details
Main Authors: Agostinho Gonçalves Viana, Luísa Mourão Dias Magalhães, Rodolfo Cordeiro Giunchetti, Walderez O. Dutra, Kenneth J. Gollob
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Leishmania
monocytes
cytokines
costimulatory molecules
protozoan parasites
pathogen immunity
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01896/full

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