Structure of human cytomegalovirus virion reveals host tRNA binding to capsid-associated tegument protein pp150

Here, cryo-EM reconstructions of human cytomegalovirus (HCMV) virions reveal host tRNAs associated with the virion’s capsid-bound tegument protein, pp150. tRNA recruitment is mediated by the interactions specific for HCMV only, suggesting the explanation for the absence of such tRNA densities in rel...

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Bibliographic Details
Main Authors: Yun-Tao Liu, David Strugatsky, Wei Liu, Z. Hong Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25791-1