Exosome-Transmitted miR-25 Induced by H. pylori Promotes Vascular Endothelial Cell Injury by Targeting KLF2

Exosome-Transmitted miR-25 Induced by H. pylori Promotes Vascular Endothelial Cell Injury by Targeting KLF2

Background: Increasing evidence has shown that Helicobacter pylori is associated with coronary heart disease (CHD); however, the underlying mechanism remains unclear.Methods: The expression of miR-25 and mRNAs was measured using qRT-PCR. Protein levels were detected using western blotting and exosom...

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Bibliographic Details
Main Authors: Na Li, Shi-feng Liu, Kai Dong, Gui-chun Zhang, Jing Huang, Zhi-heng Wang, Tong-jian Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
miR-25
Helicobacter pylori
coronary heart disease
NF-κB
KLF2
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00366/full

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