Pharmacogenomic network analysis of the gene-drug interaction landscape underlying drug disposition

In recent decades the identification of pharmacogenomic gene-drug associations has evolved tremendously. Despite this progress, a major fraction of the heritable inter-individual variability remains elusive. Higher-dimensional phenomena, such as gene-gene-drug interactions, in which variability in m...

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Bibliographic Details
Main Authors: Yitian Zhou, Volker M. Lauschke
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037019303642